Abstract Background Characterization of breast cancer (BC) through the determination of conventional markers such as ER, PR, HER2, and Ki67 has been useful as a predictive and therapeutic tool.Also, assessment of tumor-infiltrating lymphocytes has been proposed as an important prognostic aspect to be considered in certain BC subtypes.However, there
The associations of hair cortisol and DHEA with posttraumatic stress disorder symptoms in refugees
Background: Exposure to traumatic events, ongoing adversity, and posttraumatic stress disorder (PTSD) are associated with altered activity of sensory puzzle the hypothalamic-pituitary-adrenal (HPA) axis, but findings are mixed.This may be explained in part by heterogeneity in PTSD symptom profiles.Aim: The aim of this study was to investigate the c
Robust porous hydrogen-bonded organic frameworks: Synthesis and applications in gas adsorption and separation
Being an emerging family of crystalline porous materials, hydrogen-bonded organic frameworks (HOFs) are types of ordered supramolecular structures that constructed from organic linkers (including those with organometallic units) via mainly hydrogen bonds.HOFs have now attracted increasing attention in various fields, owing to their valued features
Profilin is required for viral morphogenesis, syncytium formation, and cell-specific stress fiber induction by respiratory syncytial virus
Abstract Background Actin is required for the gene expression and morphogenesis of respiratory syncytial virus (RSV), a clinically important Pneumovirus of the Paramyxoviridae family.In HEp-2 cells, RSV infection also induces actin stress fibers, which may be important in the immunopathology of the RSV disease.Profilin, a major regulator of actin p